Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 12/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432010 | 0.90 | ACE (0.42) | KLKB1CTSSCTSKMASP2KLK1 | |
| SCHEMBL1432492 | 0.90 | KLKB1 (0.43) | KLKB1CTSSCTSKMASP2KLK1 | |
| SCHEMBL1432017 | 0.90 | MME (0.43) | KLKB1MASP2KLK1NAMPT | |
| SCHEMBL1432540 | 0.89 | MASP2 (0.43) | KLKB1CTSSCTSKMASP2ANPEP | |
| SCHEMBL1432421 | 0.86 | KLKB1 (0.41) | KLKB1MASP2KLK1 | |
| SCHEMBL1432218 | 0.83 | NAMPT (0.43) | KLKB1CTSSCTSKMASP2KLK1 | |
| SCHEMBL1431651 | 0.83 | MME (0.42) | KLKB1MASP2NAMPT | |
| SCHEMBL3137896 | 0.82 | KLKB1 (0.45) | KLKB1CTSSCTSKMASP2KLK1 | |
| SCHEMBL1432675 | 0.82 | KLKB1 (0.45) | KLKB1CTSSCTSKMASP2KLK1 | |
| SCHEMBL3143740 | 0.81 | KLKB1 (0.43) | KLKB1MASP2KLK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |