Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431651 | 0.93 | MME (0.42) | MMEACECPA1ACE2KLKB1 | |
| SCHEMBL3143721 | 0.92 | KLKB1 (0.43) | MMEACECPA1ACE2KLKB1 | |
| SCHEMBL3143740 | 0.92 | KLKB1 (0.43) | MMEACECPA1ACE2KLKB1 | |
| SCHEMBL1432010 | 0.90 | ACE (0.42) | MMEACECPA1ACE2KLKB1 | |
| SCHEMBL1432152 | 0.90 | KLKB1 (0.40) | KLKB1MASP2NAMPTKLK1 | |
| SCHEMBL1431642 | 0.88 | MME (0.44) | MMEACECPA1ACE2KLKB1 | |
| SCHEMBL1431687 | 0.88 | MME (0.44) | MMEACECPA1ACE2KLKB1 | |
| SCHEMBL3140131 | 0.88 | KLKB1 (0.42) | MMEACECPA1ACE2KLKB1 | |
| SCHEMBL3140100 | 0.88 | KLKB1 (0.42) | MMEACECPA1ACE2KLKB1 | |
| SCHEMBL1432492 | 0.88 | KLKB1 (0.43) | KLKB1MASP2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | claimed |
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |