Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407909 | 0.98 | TSHR (0.51) | TSHRPTGS2KMT2AMEN1GAA | |
| SCHEMBL4399420 | 0.98 | TSHR (0.51) | TSHRPTGS2KMT2AMEN1GAA | |
| SCHEMBL4276529 | 0.95 | TSHR (0.54) | TSHRPTGS2KMT2AMEN1GAA | |
| SCHEMBL4266819 | 0.89 | GAA (0.55) | TSHRKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL26717425 | 0.81 | PTGS2 (0.54) | TSHRPTGS2KMT2AGAAL3MBTL1 | |
| SCHEMBL21102151 | 0.79 | PTGS2 (0.63) | PTGS2ALDH1A1SMN1; SMN2LTB4RHDAC3 | |
| SCHEMBL8164337 | 0.79 | TSHR (0.57) | TSHRPTGS2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4413652 | 0.78 | L3MBTL1 (0.57) | TSHRKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL31709319 | 0.78 | L3MBTL1 (0.57) | TSHRKMT2AMEN1L3MBTL1ALDH1A1 | |
| Adipic Acid SCHEMBL27952557 | 0.78 | TSHR (0.64) | TSHRKMT2AMEN1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014430-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2008-01-31 | — | — | WO | disclosed |