Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14289454 | 0.91 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL14289511 | 0.89 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL14289510 | 0.88 | TRPV1 (0.78) | TRPV1 | |
| SCHEMBL14289498 | 0.88 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL14289503 | 0.88 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL14289506 | 0.88 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL3932973 | 0.88 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL14289496 | 0.87 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL3937617 | 0.87 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL5117791 | 0.87 | TRPV1 (0.69) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004253-A1 | Thiazolopyrimidine modulators of TRPV1 | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004253-A1 | Thiazolopyrimidine modulators of TRPV1 | TRPV1, TRPA1, TRPV2 | TRPV1 1/4885FGFR1 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.