Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13776650 | 0.79 | MMP2 (0.46) | RECQLCYP3A4MEN1KMT2ABMP1 | |
| SCHEMBL4497731 | 0.77 | TSHR (0.51) | CYP3A4MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL13684193 | 0.76 | MMP2 (0.46) | TBXAS1CYP1A2MMP2HRH4HRH3 | |
| SCHEMBL13728559 | 0.75 | RECQL (0.44) | RECQLCYP3A4MEN1TP53BLM | |
| SCHEMBL13728047 | 0.74 | GRM2 (0.47) | RECQLCYP3A4MEN1TP53BLM | |
| SCHEMBL4418768 | 0.74 | RECQL (0.47) | RECQLCYP3A4MEN1TP53BLM | |
| SCHEMBL4514479 | 0.74 | SRD5A2 (0.48) | — | |
| SCHEMBL3083749 | 0.73 | L3MBTL1 (0.53) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL553604 | 0.72 | CHUK (0.53) | CYP3A4MEN1KMT2ACYP2C9MAPT | |
| SCHEMBL24658822 | 0.70 | CYP2D6 (0.34) | CYP3A4BMP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300470-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS GABA-A RECEPTOR MODULATORS | Sepracor Inc. (US) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009143156-A2 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SEPRACOR INC. (US) | 2009-11-26 | — | — | WO | disclosed |