SCHEMBL14321537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14321143	0.86	CASP3 (0.43)	RXFP1CASP3GABRA1GABRG2GABRB3
	SCHEMBL30601267	0.80	RXFP1 (0.51)	RXFP1CASP3KMT2AMEN1PKM
	SCHEMBL22400684	0.79	CASP3 (0.45)	RXFP1CASP3GABRA1GABRG2GABRB3
	SCHEMBL25955055	0.78	CYP1B1 (0.56)	RXFP1ALDH1A1CYP1B1
	SCHEMBL30676750	0.78	CYP1B1 (0.56)	RXFP1ALDH1A1CYP1B1
	SCHEMBL18938949	0.77	KDM4E (0.44)	KMT2AMEN1ALDH1A1TSHRSMN1; SMN2
	SCHEMBL18677458	0.76	HPGD (0.57)	KMT2AMEN1PKMALDH1A1NPSR1
	SCHEMBL2663790	0.75	MGAM (0.42)	RXFP1GAA
	SCHEMBL1337353	0.73	CA12 (0.57)	CASP3KMT2AMEN1ALDH1A1NPSR1
	SCHEMBL1338882	0.73	CASP3 (0.46)	CASP3GABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.