Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FPR3 | P25089 | 2/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14322164 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL608156 | 0.92 | ALDH1A1 (0.62) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL205331 | 0.92 | ALDH1A1 (0.62) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL14323243 | 0.84 | NPC1 (0.65) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL14323244 | 0.84 | NPC1 (0.65) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL28923360 | 0.83 | ALDH1A1 (0.55) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL22163586 | 0.82 | ALDH1A1 (0.63) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL13374829 | 0.81 | ALDH1A1 (0.74) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL22399147 | 0.81 | ALDH1A1 (0.62) | ALDH1A1NPC1KMT2AMEN1LMNA | |
| SCHEMBL6508896 | 0.81 | ALDH1A1 (0.64) | ALDH1A1NPC1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012175581-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-12-27 | — | — | WO | disclosed |
| US-20120328565-A1 | ANTIVIRAL COMPOUNDS | BRINKMAN JOHN A (US) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120328565-A1 | ANTIVIRAL COMPOUNDS | EIF2AK2, HAVCR2, MAVS | ALDH1A1 167/4885NPC1 108/4885KMT2A 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.