Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dinitro Cresol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitro Cresol SCHEMBL146050 | 0.96 | GPR35 (0.89) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL1260257 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL860514 | 0.95 | GPR35 (0.86) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL20474791 | 0.95 | GPR35 (0.86) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL5598346 | 0.95 | GPR35 (0.93) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL8873755 | 0.94 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL29430312 | 0.94 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL20734 | 0.94 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL9638638 | 0.93 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL711035 | 0.93 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9318765-B2 | Solid electrolyte membrane, fuel battery cell, and fuel battery | SANTOKU CORPORATION (JP) | 2016-04-19 | — | — | US | disclosed |
| EP-2544284-A1 | SOLID ELECTROLYTE MEMBRANE, FUEL BATTERY CELL, AND FUEL BATTERY | Santoku Corporation (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-20120328971-A1 | SOLID ELECTROLYTE MEMBRANE, FUEL BATTERY CELL, AND FUEL BATTERY | NATIONAL UNIV. CORPORATION HOKKAIDO UNIV. (JP) | 2012-12-27 | — | — | US | disclosed |