Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dinitro Cresol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitro Cresol SCHEMBL860514 | 0.98 | GPR35 (0.86) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL14324752 | 0.96 | GPR35 (0.89) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL711035 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL20474791 | 0.95 | GPR35 (0.86) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL1802405 | 0.95 | GPR35 (0.93) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL8873755 | 0.94 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL29430312 | 0.94 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL20734 | 0.94 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL7108490 | 0.93 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPT | |
| Dinitro Cresol SCHEMBL1260257 | 0.93 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11217796-B2 | Electrode catalyst for fuel cell and method of production of same | CATALER CORPORATION (JP) | 2022-01-04 | — | — | US | claimed |
| US-11217796-B2 | Electrode catalyst for fuel cell and method of production of same | CATALER CORPORATION (JP) | 2022-01-04 | — | — | US | disclosed |
| EP-1676622-B2 | HONEYCOMB STRUCTURE BODY | IBIDEN CO LTD (JP) | 2020-04-22 | — | — | EP | disclosed |
| US-10147956-B2 | Fuel cell electrode catalyst, production method thereof, and fuel cell | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2018-12-04 | — | — | US | disclosed |
| US-20180316024-A1 | ELECTRODE CATALYST FOR FUEL CELL AND METHOD OF PRODUCTION OF SAME | CATALER CORPORATION (JP) | 2018-11-01 | — | — | US | disclosed |
| US-20180006312-A1 | FUEL CELL ELECTRODE CATALYST, PRODUCTION METHOD THEREOF, AND FUEL CELL | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2018-01-04 | — | — | US | disclosed |
| US-9366657-B2 | Method for examining reaction layer for fuel cell | KABUSHIKI KAISHA EQUOS RESEARCH (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9180438-B2 | Wire catalyst for hydrogenation/dehydrogenation reaction and manufacturing method therefor | NIPPON SEISEN CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20140370605-A1 | METHOD FOR EXAMINING REACTION LAYER FOR FUEL CELL | KABUSHIKIKAISHA EQUOS RESEARCH (JP) | 2014-12-18 | — | — | US | disclosed |
| US-20140194273-A1 | WIRE CATALYST FOR HYDROGENATION/DEHYDROGENATION REACTION AND MANUFACTURING METHOD THEREFOR | NIPPON SEISEN CO., LTD. (JP) | 2014-07-10 | — | — | US | disclosed |
| EP-1736220-A1 | Honeycomb structured body | IBIDEN CO., LTD. (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-20060194018-A1 | Honeycomb structured body | IBIDEN CO., LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
| US-20060159602-A1 | Honeycomb structure body | IBIDEN CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1676622-A1 | HONEYCOMB STRUCTURE BODY | IBIDEN CO., LTD. (JP) | 2006-07-05 | — | — | EP | disclosed |
| EP-1676620-A1 | HONEYCOMB STRUCTURE | IBIDEN CO., LTD. (JP) | 2006-07-05 | — | — | EP | disclosed |
| EP-1626037-A1 | HONEYCOMB STRUCTURE AND METHOD FOR PRODUCING THE SAME | IBIDEN CO., LTD. (JP) | 2006-02-15 | — | — | EP | disclosed |
| US-20050247038-A1 | Honeycomb structural body and manufacturing method thereof | IBIDEN CO., LTD. (JP) | 2005-11-10 | — | — | US | disclosed |
| US-20050153099-A1 | Honeycomb filter for clarifying exhaust gases | IBIDEN CO. LTD. (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-1500799-A1 | HONEYCOMB FILTER FOR CLARIFYING EXHAUST GAS | IBIDEN CO., LTD. (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-0786285-A2 | Exhaust gas purifying catalyst, and method for purifying exhaustgas | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 1997-07-30 | — | — | EP | disclosed |