Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762665 | 0.83 | ACE (0.51) | DPP4DPP8DPP9 | |
| SCHEMBL28179500 | 0.81 | POLB (0.48) | DPP4DPP8DPP9 | |
| SCHEMBL29569595 | 0.81 | ACE (0.49) | DPP4DPP8DPP9 | |
| SCHEMBL29569572 | 0.78 | DPP4 (0.50) | DPP4DPP8DPP9 | |
| SCHEMBL29569579 | 0.78 | DPP4 (0.50) | DPP4DPP8DPP9 | |
| SCHEMBL29569145 | 0.75 | PLG (0.42) | DPP4DPP8DPP9 | |
| SCHEMBL29411140 | 0.74 | DPP4 (0.42) | DPP4DPP8DPP9 | |
| SCHEMBL5471209 | 0.74 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL8259677 | 0.74 | DPP4 (0.44) | DPP4DPP8DPP9 | |
| SCHEMBL6581948 | 0.74 | DPP4 (0.44) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338620-B2 | Methods for the production of C-8 lactam lactone compounds | NOVARTIS AG (CH) | 2012-12-25 | — | — | US | disclosed |