Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315010 | 0.90 | APLNR (0.39) | CYP11B1CYP11B2APLNR | |
| SCHEMBL315012 | 0.90 | APLNR (0.39) | CYP11B1CYP11B2APLNR | |
| SCHEMBL315011 | 0.90 | APLNR (0.39) | CYP11B1CYP11B2APLNR | |
| SCHEMBL314291 | 0.88 | CYP11B1 (0.32) | CYP11B1CYP11B2APLNRIDO1PTPN1 | |
| SCHEMBL314290 | 0.88 | CYP11B1 (0.32) | CYP11B1CYP11B2APLNRIDO1PTPN1 | |
| SCHEMBL314289 | 0.88 | CYP11B1 (0.32) | CYP11B1CYP11B2APLNRIDO1PTPN1 | |
| SCHEMBL315205 | 0.87 | HTT (0.37) | CYP11B1CYP11B2KMT2AIDO1PTPN1 | |
| SCHEMBL315203 | 0.87 | HTT (0.37) | CYP11B1CYP11B2KMT2AIDO1PTPN1 | |
| SCHEMBL315204 | 0.87 | HTT (0.37) | CYP11B1CYP11B2KMT2AIDO1PTPN1 | |
| SCHEMBL314243 | 0.86 | CYP11B2 (0.44) | CYP11B1CYP11B2APLNRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966211-B1 | TRIAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-12-26 | — | — | EP | disclosed |