Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.40 |
| ▸ | MASP2 | O00187 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431938 | 0.90 | ACE (0.45) | KLKB1MASP2MMEACECPA1 | |
| SCHEMBL1431636 | 0.89 | MME (0.43) | FURINKLKB1MASP2MMP1MME | |
| SCHEMBL1431649 | 0.89 | HTT (0.43) | FURINKLKB1MASP2MMP1 | |
| SCHEMBL1432300 | 0.85 | MASP2 (0.40) | FURINKLKB1MASP2MMP1MME | |
| SCHEMBL1432562 | 0.85 | MME (0.43) | FURINKLKB1MASP2MMP1MME | |
| SCHEMBL1434219 | 0.85 | KLKB1 (0.42) | FURINKLKB1MASP2MMP1PSMB5 | |
| SCHEMBL1432022 | 0.85 | MME (0.43) | FURINKLKB1MASP2MMP1MME | |
| SCHEMBL1431886 | 0.85 | PSMB5 (0.49) | FURINKLKB1MASP2MMEACE | |
| SCHEMBL1431722 | 0.84 | MASP2 (0.40) | FURINKLKB1MASP2MMP1 | |
| Trifluoroacetic Acid SCHEMBL1432772 | 0.83 | PSMB5 (0.43) | FURINKLKB1MASP2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |