SCHEMBL14328958

SCHEMBL14328958

Oc1cc2nc3ccccc3nc2c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 1.00
MAX P61244 1/20 1.00
MAPT P10636 3/20 0.53
ALDH1A1 P00352 2/20 0.53
GAA P10253 2/20 0.53
RAB9A P51151 2/20 0.53
KMT2A Q03164 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
TRPM4 Q8TD43 1/20 0.52
NQO2 P16083 8/20 0.46
CYP1A2 P05177 1/20 0.44
ACHE P22303 1/20 0.43
IDO1 P14902 1/20 0.41
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
RECQL P46063 1/20 0.40
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29737179 1.00 MYC (1.00) MYCMAXMAPTALDH1A1GAA
SCHEMBL29337462 0.87 MYC (0.77) MYCMAXMAPTALDH1A1GAA
SCHEMBL29337456 0.87 MYC (0.77) MYCMAXMAPTALDH1A1GAA
SCHEMBL29337586 0.81 MYC (0.67) MYCMAXMAPTALDH1A1GAA
SCHEMBL29337587 0.81 MYC (0.67) MYCMAXMAPTALDH1A1GAA
SCHEMBL29337705 0.80 MYC (0.65) MYCMAXMAPTALDH1A1GAA
SCHEMBL29337706 0.80 MYC (0.65) MYCMAXMAPTALDH1A1GAA
SCHEMBL31391239 0.78 MYC (0.63) MYCMAXMAPTALDH1A1GAA
SCHEMBL30705441 0.78 MYC (0.63) MYCMAXMAPTALDH1A1GAA
SCHEMBL14328966 0.76 MYC (0.61) MYCMAXMAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240243319-A1 AQUEOUS ELECTROLYTE, SALTS USED THEREIN, AND REDOX FLOW BATTERY USING SAID AQUEOUS ELECTROLYTE MITSUBISHI CHEMICAL CORPORATION (JP) 2024-07-18 US disclosed
US-10553799-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170365794-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-12-21 US disclosed
US-20170365794-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-12-21 US disclosed
US-9522124-B2 Methods for treating Alzheimer's disease WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-12-20 US disclosed
US-9522124-B2 Methods for treating Alzheimer's disease WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-12-20 US disclosed
US-20150182477-A1 Compositions and Methods for Treating Alzheimers Disease WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-07-02 US disclosed
US-20150182477-A1 Compositions and Methods for Treating Alzheimers Disease WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-07-02 US disclosed
US-8980884-B2 Methods for treating Alzheimer's disease WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-03-17 US disclosed
US-8980884-B2 Methods for treating Alzheimer's disease WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-03-17 US disclosed
US-20120329789-A1 COMPOSITIONS AND METHODS FOR TREATING ALZHEIMERS DISEASE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-12-27 US disclosed
US-20120329789-A1 COMPOSITIONS AND METHODS FOR TREATING ALZHEIMERS DISEASE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120329789-A1 COMPOSITIONS AND METHODS FOR TREATING ALZHEIMERS DISEASE BACE1, APP, PSEN2 MYC 2893/4885MAX 2413/4885MAPT 21/4885
US-20170365794-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNA1 MYC 1301/4885MAX 3882/4885MAPT 1538/4885
US-20150182477-A1 Compositions and Methods for Treating Alzheimers Disease BACE1, APP, PSEN2 MYC 2893/4885MAX 2413/4885MAPT 21/4885
US-10553799-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNA1 MYC 1301/4885MAX 3882/4885MAPT 1538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.