SCHEMBL14330855

SCHEMBL14330855

CNCCCCCCOP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)CC1O

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.67
▸ P2RY2 P41231 1/20 0.65
▸ P2RY4 P51582 1/20 0.65
▸ P2RY6 Q15077 1/20 0.65
▸ KRAS P01116 6/20 0.57
▸ FUT5 Q11128 1/20 0.55
▸ TGM2 P21980 1/20 0.54
▸ DTYMK P23919 4/20 0.50
▸ NT5E P21589 2/20 0.48
▸ POLG P54098 1/20 0.47
▸ TAS1R3 Q7RTX0 1/20 0.47
▸ TAS1R1 Q7RTX1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16609774 0.92 POLB (0.65) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL10077355 0.92 POLB (0.70) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL19418709 0.92 POLB (0.70) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL10055580 0.92 POLB (0.70) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL23366177 0.91 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL16280921 0.91 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL13127150 0.91 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL10055280 0.91 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL13111577 0.91 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL23901144 0.90 POLB (0.72) POLBP2RY2P2RY4P2RY6KRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695471-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2017-07-04 — — US disclosed
US-20150118679-A1 METHODS AND APPARATUS FOR SINGLE MOLECULE SEQUENCING USING ENERGY TRANSFER DETECTION Life Technologies Corporation 2015-04-30 — — US disclosed
US-8999674-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2015-04-07 — — US disclosed
US-20120329042-A1 METHODS AND APPARATUS FOR SINGLE MOLECULE SEQUENCING USING ENERGY TRANSFER DETECTION Life Technologies Corporation (US) 2012-12-27 — — US disclosed
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