SCHEMBL23366177

SCHEMBL23366177

NCCCCCCOP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OCC1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)C[C@H]1O

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.71
▸ P2RY2 P41231 2/20 0.68
▸ P2RY4 P51582 2/20 0.68
▸ P2RY6 Q15077 2/20 0.68
▸ KRAS P01116 4/20 0.56
▸ FUT5 Q11128 1/20 0.55
▸ TGM2 P21980 1/20 0.55
▸ NT5E P21589 2/20 0.51
▸ DTYMK P23919 4/20 0.51
▸ POLG P54098 1/20 0.49
▸ PNP P00491 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13127150 1.00 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL13111577 1.00 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL16280921 1.00 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL10055280 1.00 POLB (0.71) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL18959632 0.93 POLB (0.61) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL10055580 0.93 POLB (0.70) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL10077355 0.93 POLB (0.70) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL19418709 0.93 POLB (0.70) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL10055236 0.92 POLB (0.61) POLBP2RY2P2RY4P2RY6KRAS
SCHEMBL16280903 0.92 POLB (0.61) POLBP2RY2P2RY4P2RY6KRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11008612-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2021-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11008612-B2 Methods and apparatus for single molecule sequencing using energy transfer detection POLRMT, DNTT, POLM POLB 6/4885P2RY2 1235/4885P2RY4 1103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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