Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.68 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.68 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.68 |
| ▸ | KRAS | P01116 | 4/20 | 0.56 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | DTYMK | P23919 | 4/20 | 0.51 |
| ▸ | POLG | P54098 | 1/20 | 0.49 |
| ▸ | PNP | P00491 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13127150 | 1.00 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL13111577 | 1.00 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL23366177 | 1.00 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL16280921 | 1.00 | POLB (0.71) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL18959632 | 0.93 | POLB (0.61) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL10055580 | 0.93 | POLB (0.70) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL10077355 | 0.93 | POLB (0.70) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL19418709 | 0.93 | POLB (0.70) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL10055236 | 0.92 | POLB (0.61) | POLBP2RY2P2RY4P2RY6KRAS | |
| SCHEMBL16280903 | 0.92 | POLB (0.61) | POLBP2RY2P2RY4P2RY6KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9702001-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9702001-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20150307933-A1 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
| US-8906612-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20120077189-A1 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120077189-A1 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077189-A1 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | POLM, RNGTT, POLR1G | POLB 12/4885P2RY2 3260/4885P2RY4 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.