SCHEMBL14330858

SCHEMBL14330858

Cc1cn(C[C@H]2CC(O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OCCCCCCN)O2)c(=O)[nH]c1=O

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.51
▸ DTYMK P23919 4/20 0.48
▸ POLA1 P09884 1/20 0.46
▸ POLD1 P28340 1/20 0.46
▸ TYMS P04818 1/20 0.44
▸ TK1 P04183 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19135278 0.87 POLB (0.66) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL21896795 0.87 POLB (0.66) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL19661255 0.87 POLB (0.66) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL26033337 0.87 POLB (0.66) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL13127048 0.87 POLB (0.66) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL13111576 0.87 POLB (0.66) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL19663814 0.87 POLB (0.66) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL14599412 0.84 POLB (0.71) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL14138785 0.84 POLB (0.71) POLBDTYMKPOLA1POLD1TYMS
SCHEMBL14330854 0.80 POLB (0.51) POLBPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999674-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2015-04-07 — — US disclosed
US-20120329042-A1 METHODS AND APPARATUS FOR SINGLE MOLECULE SEQUENCING USING ENERGY TRANSFER DETECTION Life Technologies Corporation (US) 2012-12-27 — — US disclosed
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