SCHEMBL14330854

SCHEMBL14330854

NCCCCCCOP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](Cn2ccc(N)nc2=O)CC1O

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.51
▸ P2RY2 P41231 7/20 0.51
▸ P2RY4 P51582 5/20 0.51
▸ P2RY6 Q15077 4/20 0.51
▸ POLG P54098 1/20 0.44
▸ FGFR1 P11362 3/20 0.42
▸ TRPM2 O94759 2/20 0.39
▸ P2RY12 Q9H244 2/20 0.39
▸ POLA1 P09884 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13111591 0.86 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL13127046 0.86 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL145870 0.86 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL14330858 0.80 POLB (0.51) POLBPOLA1
SCHEMBL14330856 0.80 TRPM2 (0.62) POLBP2RY2TRPM2
SCHEMBL143835 0.79 P2RY2 (0.57) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL10053783 0.78 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL19412517 0.77 P2RY2 (0.57) POLBP2RY2P2RY4P2RY6POLG
Deoxycytidine Triphosphate SCHEMBL703664 0.76 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
Deoxycytidine Triphosphate SCHEMBL18785037 0.76 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999674-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2015-04-07 — — US disclosed
US-20120329042-A1 METHODS AND APPARATUS FOR SINGLE MOLECULE SEQUENCING USING ENERGY TRANSFER DETECTION Life Technologies Corporation (US) 2012-12-27 — — US disclosed
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