Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 2/20 | 0.45 |
| ▸ | IL2 | P60568 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433480 | 0.90 | MCHR1 (0.48) | MCHR1CTNNB1PYGLALBIL2 | |
| SCHEMBL1433228 | 0.88 | PYGL (0.49) | MCHR1CTNNB1PYGLALBIL2 | |
| SCHEMBL1433942 | 0.88 | CTNNB1 (0.54) | MCHR1CTNNB1PYGLALBIL2 | |
| SCHEMBL1433787 | 0.87 | MCHR1 (0.50) | MCHR1CTNNB1PYGLALBIL2 | |
| SCHEMBL1433255 | 0.87 | F2 (0.52) | MCHR1MAPK14CTNNB1PYGLALB | |
| SCHEMBL3145207 | 0.86 | MAPK14 (0.48) | MCHR1MAPK14CNR2CTSL | |
| SCHEMBL1433846 | 0.86 | MCHR1 (0.49) | MCHR1CTNNB1PYGLALBIL2 | |
| SCHEMBL1433066 | 0.85 | MAPK14 (0.47) | MCHR1MAPK14CTSL | |
| SCHEMBL1432911 | 0.84 | MCHR1 (0.49) | MCHR1CTNNB1PYGLALBIL2 | |
| SCHEMBL1433134 | 0.84 | MCHR1 (0.47) | MCHR1CTNNB1PYGLALBIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |