Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | MASP2 | O00187 | 3/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 3/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434686 | 0.90 | MCHR1 (0.55) | F2MASP2MCHR1PYGLCTNNB1 | |
| SCHEMBL1433599 | 0.90 | PYGL (0.50) | F2MASP2PYGLCTNNB1ALB | |
| SCHEMBL1433554 | 0.88 | PYGL (0.52) | F2PYGLCTNNB1CTSLCTSS | |
| SCHEMBL1433128 | 0.87 | MCHR1 (0.56) | MCHR1PYGLCTNNB1CTSLCTSS | |
| SCHEMBL1433141 | 0.86 | MCHR1 (0.48) | F2MASP2MCHR1PYGLCTSL | |
| SCHEMBL1433111 | 0.85 | F2 (0.53) | F2MASP2CTSLMAPK14 | |
| SCHEMBL1433165 | 0.85 | F2 (0.49) | F2MCHR1PYGLCTNNB1ALB | |
| SCHEMBL1433349 | 0.84 | F2 (0.51) | F2MASP2MCHR1PYGLCTNNB1 | |
| SCHEMBL1433514 | 0.81 | CCKBR (0.57) | CTSL | |
| SCHEMBL3157965 | 0.80 | F2 (0.60) | F2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |