Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | MASP2 | O00187 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432208 | 0.90 | TACR1 (0.44) | TACR1MASP2KMT2AMEN1PPIB | |
| SCHEMBL1431988 | 0.90 | TACR1 (0.44) | TACR1MASP2 | |
| SCHEMBL1432725 | 0.90 | TACR1 (0.46) | TACR1MASP2XIAP | |
| SCHEMBL1433336 | 0.89 | TACR1 (0.46) | TACR1MASP2PPIBNTMT1 | |
| SCHEMBL1431638 | 0.88 | DPP4 (0.40) | MASP2KMT2AMEN1PPIBDPP4 | |
| SCHEMBL1432180 | 0.88 | DPP4 (0.40) | MASP2KMT2AMEN1PPIBDPP4 | |
| SCHEMBL1431814 | 0.88 | MEN1 (0.48) | TACR1MASP2KMT2AMEN1PPIB | |
| SCHEMBL1432532 | 0.88 | MEN1 (0.48) | TACR1MASP2KMT2AMEN1PPIB | |
| Hydrochloric Acid SCHEMBL1432515 | 0.88 | DPP4 (0.40) | MASP2KMT2AMEN1PPIBDPP4 | |
| SCHEMBL1431888 | 0.87 | MASP2 (0.40) | TACR1MASP2KMT2AMEN1PPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |