Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432145 | 0.91 | TACR1 (0.46) | TACR1NTMT1FNTAPGGT1BMASP2 | |
| SCHEMBL1433133 | 0.89 | TACR1 (0.43) | TACR1NTMT1MASP2PPIB | |
| SCHEMBL1431988 | 0.89 | TACR1 (0.44) | TACR1MASP2 | |
| SCHEMBL1432848 | 0.87 | KLKB1 (0.47) | MASP2PPIBOPRD1OPRM1CTSS | |
| SCHEMBL1432725 | 0.87 | TACR1 (0.46) | TACR1MASP2PLGPRSS1PRSS2 | |
| SCHEMBL1432873 | 0.87 | F2 (0.52) | TACR1NTMT1MASP2P2RX7F2 | |
| SCHEMBL13623819 | 0.87 | F2 (0.52) | TACR1NTMT1MASP2P2RX7F2 | |
| SCHEMBL1433724 | 0.87 | TACR1 (0.48) | TACR1 | |
| SCHEMBL1905233 | 0.86 | NTMT1 (0.44) | TACR1NTMT1FNTAPGGT1BLCK | |
| SCHEMBL1906955 | 0.86 | NTMT1 (0.44) | TACR1NTMT1FNTAPGGT1BLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |