Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335042 | 0.87 | LMNA (0.47) | LMNAMEN1KMT2ATSHRALOX12 | |
| SCHEMBL14335596 | 0.84 | HPGD (0.58) | MEN1KMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL14334977 | 0.84 | MEN1 (0.44) | LMNAMEN1KMT2ATSHRALOX12 | |
| SCHEMBL14335640 | 0.83 | LMNA (0.48) | LMNAMEN1KMT2ATSHRALOX12 | |
| SCHEMBL14334940 | 0.83 | LMNA (0.46) | LMNAMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14335757 | 0.82 | MEN1 (0.53) | LMNAMEN1KMT2ATSHRALOX12 | |
| SCHEMBL14335061 | 0.82 | HPGD (0.46) | LMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL14335777 | 0.82 | HPGD (0.46) | HPGDALDH1A1L3MBTL1KDM4EUSP2 | |
| SCHEMBL15709924 | 0.81 | SLC6A4 (0.44) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL14335193 | 0.81 | LMNA (0.53) | LMNAMEN1KMT2ATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723780-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2017-04-26 | — | — | EP | disclosed |
| US-9034783-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2015-05-19 | — | — | US | disclosed |
| US-20140142262-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.I. (IT) | 2014-05-22 | — | — | US | disclosed |
| EP-2723780-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2014-04-30 | — | — | EP | disclosed |
| WO-2012175425-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2012-12-27 | — | — | WO | disclosed |