Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477067 | 0.78 | DRD2 (0.53) | GRM5DRD2DRD3NSD2MAPT | |
| SCHEMBL17632724 | 0.74 | GRM5 (0.62) | GRM5DRD2DRD3NSD2MAPT | |
| SCHEMBL1434069 | 0.74 | FAAH (0.46) | MAPTNOTUMC1S | |
| SCHEMBL28226742 | 0.73 | GRM5 (0.48) | GRM5DRD2DRD3NSD2NOTUM | |
| SCHEMBL27858736 | 0.73 | GRM5 (0.48) | GRM5DRD2DRD3NOTUM | |
| SCHEMBL28226586 | 0.73 | GRM5 (0.48) | GRM5DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL25192250 | 0.73 | GRM5 (0.60) | GRM5DRD2DRD3NSD2MAPT | |
| Hydrochloric Acid SCHEMBL31095460 | 0.73 | GRM5 (0.60) | GRM5DRD2DRD3NSD2MAPT | |
| SCHEMBL1351786 | 0.72 | COMT (0.48) | MAPT | |
| SCHEMBL5100840 | 0.71 | GRM5 (1.00) | GRM5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300457-A1 | SUBSTITUTED PYRROLES AND METHODS OF USE | Genentech, Inc. (US) | 2011-03-30 | — | — | EP | disclosed |