SCHEMBL14335166

SCHEMBL14335166

O=C(N[C@@H](Cc1ccccc1)P(=O)(O)O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.58
CTRB1 P17538 5/20 0.58
PTPN1 P18031 1/20 0.51
LAP3 P28838 3/20 0.50
CTSL P07711 3/20 0.50
ANPEP P15144 1/20 0.50
PLG P00747 1/20 0.50
PLAU P00749 1/20 0.50
CTSS P25774 1/20 0.50
CTSK P43235 1/20 0.50
HPGD P15428 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
ACE P12821 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14335286 0.83 CTRB1 (0.55) CTRB1LAP3ANPEPPLGPLAU
SCHEMBL2240047 0.83 PLG (0.48) PIN1CTRB1PTPN1CTSLPLG
SCHEMBL8681583 0.81 PLG (0.55) PIN1CTRB1PTPN1LAP3CTSL
SCHEMBL14377773 0.79 SMN1; SMN2 (0.60) PIN1CTRB1CTSLPLGPLAU
SCHEMBL19615782 0.79 ANPEP (0.53) LAP3ANPEPPLGPLAU
SCHEMBL14334539 0.78 ECE1 (0.63) CTRB1PLGPLAU
SCHEMBL1582144 0.78 CTRB1 (0.59) CTRB1LAP3ANPEPNPC1RAB9A
SCHEMBL1791566 0.78 ACE (0.61) PIN1CTRB1PTPN1CTSLCTSS
SCHEMBL7328702 0.78 ECE1 (0.63) CTRB1PLGPLAU
SCHEMBL1813322 0.77 CTRB1 (0.63) PIN1CTRB1PTPN1CTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2723701-A1 PROCESSES FOR PREPARING PHOSPHORUS-CONTAINING ALPHA- AND BETA-AMINO ACIDS AND DERIVATIVES THEREOF Diverchim (FR) 2014-04-30 EP disclosed
WO-2012175837-A1 PROCESSES FOR PREPARING PHOSPHORUS-CONTAINING Α- AND Β-AMINO ACIDS AND DERIVATIVES THEREOF DIVERCHIM (FR) 2012-12-27 WO disclosed