Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335979 | 0.83 | DYRK1A (0.39) | DYRK1AARPRMT5WDR77TGFBR1 | |
| SCHEMBL2053284 | 0.74 | DYRK1A (0.40) | DYRK1A | |
| SCHEMBL14375504 | 0.74 | DYRK1A (0.49) | DYRK1AGAAKMT2APRMT5WDR77 | |
| SCHEMBL14335966 | 0.73 | DYRK1A (0.42) | DYRK1AAR | |
| SCHEMBL23986239 | 0.72 | RAB9A (0.47) | DYRK1AALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL27015063 | 0.72 | DYRK1A (0.48) | DYRK1AGAAHPGDALDH1A1HTT | |
| SCHEMBL27015076 | 0.71 | PDE10A (0.45) | DYRK1AHPGDALDH1A1KMT2AKDM4E | |
| SCHEMBL2051388 | 0.71 | DYRK1A (0.40) | DYRK1A | |
| SCHEMBL14336174 | 0.70 | GAA (0.40) | GAAAPOBEC3GHPGDALDH1A1ALOX12 | |
| SCHEMBL16911874 | 0.70 | ESR2 (0.41) | DYRK1AARPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012175513-A1 | THIENYLPYRI(MI)DINYLPYRAZOLE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-27 | — | — | WO | disclosed |