Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051571 | 0.85 | MET (0.39) | METTDP2HPGDSKDM5BGRIN2B | |
| SCHEMBL2051388 | 0.84 | DYRK1A (0.40) | DYRK1ATDP2BACE1 | |
| SCHEMBL14335673 | 0.74 | DYRK1A (0.40) | DYRK1A | |
| SCHEMBL27015063 | 0.72 | DYRK1A (0.48) | DYRK1AKDM5B | |
| SCHEMBL2050809 | 0.72 | MET (0.40) | METTDP2GRIN2BGRIN1BACE1 | |
| SCHEMBL27015076 | 0.71 | PDE10A (0.45) | DYRK1AIRAK4GABRA1GABRG2GABRB3 | |
| SCHEMBL2609419 | 0.70 | DYRK1A (0.45) | DYRK1A | |
| SCHEMBL2050710 | 0.70 | DYRK1A (0.39) | DYRK1A | |
| SCHEMBL14335979 | 0.70 | DYRK1A (0.39) | DYRK1AGRIN2B | |
| SCHEMBL2054185 | 0.70 | TDP2 (0.37) | TDP2KDM5BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516423-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| CN-102762551-A | Thienylpyri (mi) dinylpyrazoles and their use for controlling phytopathogenic fungi | BAYER CROPSCIENCE AG | 2012-10-31 | — | — | CN | disclosed |
| US-20110237588-A1 | Thienylpyri(mi)dinylazole | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| WO-2011076725-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237588-A1 | Thienylpyri(mi)dinylazole | PADI1, TH, H1-3 | DYRK1A 1013/4885MET 3340/4885TDP2 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.