Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | CA7 | P43166 | 5/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651635 | 0.92 | TSHR (0.43) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL19508782 | 0.92 | TSHR (0.43) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL19106903 | 0.92 | TSHR (0.43) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL1142641 | 0.89 | TSHR (0.42) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 | |
| Water SCHEMBL11650852 | 0.89 | TSHR (0.42) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL24635151 | 0.89 | TSHR (0.48) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL19509181 | 0.89 | TSHR (0.42) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL17280409 | 0.87 | TSHR (0.40) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL20807295 | 0.86 | — | — | |
| SCHEMBL10676068 | 0.84 | TSHR (0.42) | TSHRHPGDSMN1; SMN2NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279214-A1 | FOAMABLE ACRYLIC COMPOSITION | ARKEMA FRANCE (FR) | 2023-09-07 | — | — | US | claimed |
| EP-3717554-A1 | FOAMABLE ACRYLIC COMPOSITION | Arkema, Inc. (US) | 2020-10-07 | — | — | EP | claimed |
| US-20200282689-A1 | MULTI-LAYER FLUOROPOLYMER FOAM STRUCTURE | ARKEMA INC (US) | 2020-09-10 | — | — | US | claimed |
| EP-2888515-A2 | MULTI-LAYER FLUOROPOLYMER FOAM STRUCTURE | Arkema, Inc. (US) | 2015-07-01 | — | — | EP | claimed |
| WO-2014031510-A2 | MULTI-LAYER FLUOROPOLYMER FOAM STRUCTURE | ARKEMA INC. (US) | 2014-02-27 | — | — | WO | claimed |
| US-20130108816-A1 | MULTI-LAYER FLUOROPOLYMER FOAM STRUCTURE | ARKEMA INC. (US) | 2013-05-02 | — | — | US | claimed |
| EP-0214552-B1 | FOAMABLE MOLDINGS COMPOSITIONS | MOBAY CORPORATION (US) | 1990-09-26 | — | — | EP | claimed |
| US-4737523-A | BLEND CONTAINING ANHYDRIDE-IMPACT RESISTANCE | MOBAY CORPORATION (US) | 1988-04-12 | — | — | US | claimed |
| US-4675345-A | JACKETS AND COATINGS FOR CABLES AND TELEPHONE WIRES; DIELECTR ICS | PENWALT CORPORATION (US) | 1987-06-23 | — | — | US | claimed |
| EP-0214552-A2 | Foamable moldings compositions | MOBAY CORPORATION (US) | 1987-03-18 | — | — | EP | claimed |
| US-4615850-A | BLENDING WITH NUCLEATING AGENT, BLOWING AGENT; EXTRUSION | PENNWALT CORPORATION (US) | 1986-10-07 | — | — | US | claimed |
| EP-0169304-A1 | Foamable polyvinylidene fluoride and a method for producing it | PENNWALT CORPORATION (US) | 1986-01-29 | — | — | EP | claimed |
| US-4394460-A | WIRE COATINGS | ALLIED CORPORATION (US) | 1983-07-19 | — | — | US | claimed |
| US-20260144795-A1 | SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS | H. LUNDBECK A/S (DK) | 2026-05-28 | — | — | US | disclosed |
| EP-4720076-A1 | SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS | H. Lundbeck A/S (DK) | 2026-04-08 | — | — | EP | disclosed |
| US-12590106-B2 | Spiromacrocyclic orexin 2 receptor agonists | H. LUNDBECK A/S (DK) | 2026-03-31 | — | — | US | disclosed |
| US-4334030-A | INJECTION MOLDABLE CONCENTRATES CONTAINING AMIDE DERIVATIVES OF AZODICARBOXYLIC ACID AND A DIHYDROOXADIAZINONE AS BLOWING AGENTS | GENERAL ELECTRIC COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4331619-A | Ethylene-chlorotrifluoroethylene copolymer foam | ALLIED CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| US-4163037-A | USING A DIHYDROOXADIAZINONE BLOWING AGENT, INJECTION MOLDING | GENERAL ELECTRIC COMPANY (US) | 1979-07-31 | — | — | US | disclosed |
| US-4097425-A | POLYCARBONATES, POLYESTERS, SUBSTITUTED 3,6-DIHYDRO-1,3,4-OXDIAZIN-2-ONE | GENERAL ELECTRIC COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260144795-A1 | SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS | HCRTR2, HCRTR1, CRHR1 | TSHR 119/4885HPGD 1531/4885SMN1; SMN2 2566/4885 |
| US-12590106-B2 | Spiromacrocyclic orexin 2 receptor agonists | HCRTR2, HCRTR1, OXER1 | TSHR 255/4885HPGD 499/4885SMN1; SMN2 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.