SCHEMBL19106903

SCHEMBL19106903

CC(C)OC(=O)NNC(=O)OOC(=O)NNC(=O)OOC(=O)NNC(=O)OC(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
RAB9A P51151 1/20 0.38
KDM4E B2RXH2 1/20 0.36
CA12 O43570 5/20 0.35
CA1 P00915 5/20 0.35
CA2 P00918 5/20 0.35
CA7 P43166 5/20 0.35
CA9 Q16790 5/20 0.35
CA14 Q9ULX7 5/20 0.35
ALOX15 P16050 2/20 0.35
HCAR2 Q8TDS4 1/20 0.34
HTT P42858 1/20 0.34
GAA P10253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143364 0.92 TSHR (0.50) TSHRHPGDSMN1; SMN2NPC1CYP1A2
SCHEMBL11651635 0.84 TSHR (0.43) TSHRHPGDSMN1; SMN2NPC1CYP1A2
SCHEMBL19508782 0.84 TSHR (0.43) TSHRHPGDSMN1; SMN2NPC1CYP1A2
Water SCHEMBL11650852 0.82 TSHR (0.42) TSHRHPGDSMN1; SMN2NPC1CYP1A2
SCHEMBL1142641 0.82 TSHR (0.42) TSHRHPGDSMN1; SMN2NPC1CYP1A2
SCHEMBL24635151 0.82 TSHR (0.48) TSHRHPGDSMN1; SMN2NPC1CYP1A2
SCHEMBL19509181 0.82 TSHR (0.42) TSHRHPGDSMN1; SMN2NPC1CYP1A2
SCHEMBL19106902 0.81 TSHR (0.30) TSHR
SCHEMBL17280409 0.80 TSHR (0.40) TSHRHPGDSMN1; SMN2NPC1CYP1A2
SCHEMBL821023 0.80 CHRNB2 (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170198085-A1 POLYURETHANE-MODIFIED EPOXY RESIN, METHOD FOR PRODUCING SAME, EPOXY RESIN COMPOSITION AND CURED PRODUCT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2017-07-13 US disclosed