SCHEMBL1433669

SCHEMBL1433669

C=CC(=O)OCCCCN1CC1

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.64
ALDH1A1 P00352 5/20 0.64
CYP3A4 P08684 2/20 0.64
HPGD P15428 1/20 0.53
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
HSD17B10 Q99714 1/20 0.48
SLC29A1 Q99808 2/20 0.42
TEAD3 Q99594 1/20 0.40
THRB P10828 2/20 0.38
BCHE P06276 2/20 0.37
PAOX Q6QHF9 1/20 0.37
MEN1 O00255 1/20 0.37
RAD52 P43351 1/20 0.37
KMT2A Q03164 1/20 0.37
RAB9A P51151 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9314283 0.98 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9315129 0.98 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7085762 0.94 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25561202 0.92 ALDH1A1 (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL30980880 0.91 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL11313067 0.91 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25165772 0.91 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10716218 0.89 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27756363 0.87 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL12860037 0.86 ALDH1A1 (0.54) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138934-B1 ACRYLIC TELOMERS WITH PHOTOCROSSLINKABLE GRAFTS, SYNTHESIS THEREOF AND THEIR APPLICATIONS TO THE COATING OF METALS Société Anonyme dite: NORSOLOR (FR) 1989-03-15 EP claimed
US-4638018-A Acrylic telomers with grafts which can be cross linked by light, their synthesis and their applications in coating metals CEGEDUR SOCIETE DE TRANSFORMATION DE L'ALUMINIUM PECHINEY (FR) 1987-01-20 US claimed
US-12404419-B2 Imide addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-09-02 US disclosed
US-12398301-B2 Adhesives comprising cyclic imide addition-fragmentation and adhesion agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-08-26 US disclosed
US-12329833-B2 Dental compositions SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-06-17 US disclosed
US-20250049644-A1 Dental Compositions SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-02-13 US disclosed
US-20250011633-A1 Adhesives Comprising Cyclic Imide Addition-Fragmentation And Adhesion Agents 3M INNOVATIVE PROPERTIES COMPANY 2025-01-09 US disclosed
EP-4444809-A1 ADHESIVES COMPRISING CYCLIC IMIDE ADDITION-FRAGMENTATION AND ADHESION AGENTS 3M Innovative Properties Company (US) 2024-10-16 EP disclosed
EP-4444250-A1 DENTAL COMPOSITIONS Solventum Intellectual Properties Company (US) 2024-10-16 EP disclosed
US-20230323151-A1 IMIDE ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2023-10-12 US disclosed
WO-2023105315-A1 DENTAL COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-06-15 WO disclosed
EP-1819737-B1 PHOTOCURABLE MICHAEL ADDITION POLYMERS 3M INNOVATIVE PROPERTIES CO (US) 2011-03-30 EP disclosed
CN-101076545-B Photohardenable michael adduct polymer 3M INNOVATIVE PROPERTIES CO 2011-03-02 CN disclosed
US-7307106-B2 Photocurable Michael addition polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-12-11 US disclosed
CN-101076545-A Photohardenable michael adduct polymer 3M INNOVATIVE PROPERTIES CO (US) 2007-11-21 CN disclosed
EP-1819737-A2 PHOTOCURABLE MICHAEL ADDITION POLYMERS 3M Innovative Properties Company (US) 2007-08-22 EP disclosed
WO-2006065369-A2 PHOTOCURABLE MICHAEL ADDITION POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-22 WO disclosed
US-20060128825-A1 Photocurable michael addition polymers 3M INNOVATIVE PROPERTIES COMPANY 2006-06-15 US disclosed
US-5315031-A Oligomers with polydiene sequences and photocrosslinkable grafts and their application particularly in coating metals ATOCHEM (FR) 1994-05-24 US disclosed
US-4638018-A Acrylic telomers with grafts which can be cross linked by light, their synthesis and their applications in coating metals CEGEDUR SOCIETE DE TRANSFORMATION DE L'ALUMINIUM PECHINEY (FR) 1987-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049644-A1 Dental Compositions ARCN1, EEF1D, EBP TSHR 4746/4885ALDH1A1 1021/4885CYP3A4 2966/4885
US-12329833-B2 Dental compositions ARCN1, EEF1D, EBP TSHR 4746/4885ALDH1A1 1021/4885CYP3A4 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.