Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.41 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315129 | 1.00 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1433669 | 0.98 | TSHR (0.64) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25561202 | 0.94 | ALDH1A1 (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL11313067 | 0.93 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL30980880 | 0.93 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7085762 | 0.93 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25165772 | 0.92 | TSHR (0.58) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL10716218 | 0.87 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28985923 | 0.86 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL27756363 | 0.86 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138934-B1 | ACRYLIC TELOMERS WITH PHOTOCROSSLINKABLE GRAFTS, SYNTHESIS THEREOF AND THEIR APPLICATIONS TO THE COATING OF METALS | Société Anonyme dite: NORSOLOR (FR) | 1989-03-15 | — | — | EP | claimed |
| US-4638018-A | Acrylic telomers with grafts which can be cross linked by light, their synthesis and their applications in coating metals | CEGEDUR SOCIETE DE TRANSFORMATION DE L'ALUMINIUM PECHINEY (FR) | 1987-01-20 | — | — | US | claimed |
| US-5315031-A | Oligomers with polydiene sequences and photocrosslinkable grafts and their application particularly in coating metals | ATOCHEM (FR) | 1994-05-24 | — | — | US | disclosed |
| US-4638018-A | Acrylic telomers with grafts which can be cross linked by light, their synthesis and their applications in coating metals | CEGEDUR SOCIETE DE TRANSFORMATION DE L'ALUMINIUM PECHINEY (FR) | 1987-01-20 | — | — | US | disclosed |