SCHEMBL1433697

SCHEMBL1433697

CCC(Oc1ccccc1)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
NPSR1 Q6W5P4 1/20 0.49
PPARG P37231 4/20 0.48
PPARA Q07869 4/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HSD17B10 Q99714 2/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361229 0.85 ALDH1A1 (0.59) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL295888 0.85 SMN1; SMN2 (0.64) ALDH1A1TSHRPPARGPPARASMN1; SMN2
SCHEMBL4651839 0.85 SMN1; SMN2 (0.64) ALDH1A1TSHRPPARGPPARASMN1; SMN2
Hydrochloric Acid SCHEMBL30415831 0.84 PPARG (0.55) ALDH1A1TSHRPPARGPPARA
SCHEMBL16242049 0.84 PPARG (0.51) ALDH1A1TSHRPPARGPPARASMN1; SMN2
SCHEMBL13322046 0.83 ALDH1A1 (0.54) ALDH1A1TSHRNPSR1PPARGPPARA
Hydrochloric Acid SCHEMBL11617632 0.83 SMN1; SMN2 (0.62) ALDH1A1TSHRPPARGPPARASMN1; SMN2
SCHEMBL11131627 0.83 ALDH1A1 (0.54) ALDH1A1TSHRNPSR1PPARGPPARA
SCHEMBL15333872 0.83 PARP1 (0.51) ALDH1A1TSHRLMNAL3MBTL1
SCHEMBL11664164 0.82 CTSK (0.50) PPARGPPARAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080161325-A1 e.g. N1-[3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]-3-(butylsulfonyl)-N1-(3-ethylbenzyl)-D-alaninamide dihydrochloride; inhibitors of amyloid beta-secretase enzyme; neurodegenerative diseases: Alzheimer's, Parkinson's diseases, Down's syndrome ELAN PHARMACEUTICALS, INC. 2008-07-03 US claimed
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 US claimed
WO-1999039207-A1 ACID CLEAVABLE PHENOXYALKYL LINKER FOR COMBINATORIAL SYNTHESIS PHARMACOPEIA, INC. (US) 1999-08-05 WO claimed
WO-2026021913-A1 Herbicidal 2-phenoxybutanoylamides BASF SE (DE) 2026-01-29 WO disclosed
CN-113056196-B Compositions comprising picolinate herbicides with glyphosate or glufosinate 科迪华农业科技有限责任公司 2024-04-02 CN disclosed
CN-117813004-A Auxin herbicide and application method thereof 科迪华农业科技有限责任公司 2024-04-02 CN disclosed
CN-113453551-B Compositions comprising pyridine carboxylic acid herbicides and azole carboxylic acid safeners 科迪华农业科技有限责任公司 2023-10-13 CN disclosed
CN-116806118-A Method for controlling weed growth and composition comprising herbicidally active compound and thiocyanate compound 马斯特格罗生物制品公司 2023-09-26 CN disclosed
CN-112969370-B Compositions comprising pyridine carboxylic acid herbicides and PDS inhibitor herbicides 科迪华农业科技有限责任公司 2023-08-04 CN disclosed
CN-113453550-B Safening compositions comprising pyridine carboxylic acid herbicides and quinoxaline acetic acid 科迪华农业科技有限责任公司 2023-06-13 CN disclosed
CN-112955011-B Compositions comprising pyridine carboxylic acid herbicides with photosystem II and optionally HPPD inhibitor herbicides 科迪华农业科技有限责任公司 2023-06-02 CN disclosed
US-5276192-A Preparation of phenoxyethanamines TEXACO CHEMICAL COMPANY (US) 1994-01-04 US disclosed
US-5187053-A Storage stability FUJI PHOTO FILM CO., LTD. (JP) 1993-02-16 US disclosed
US-5037733-A High speed, storage stable photographic films and papers, surface bromination of silver halide grains, cyanine dyes FUJI PHOTO FILM CO., LTD. (JP) 1991-08-06 US disclosed
US-4929273-A N-benzyl-2-(4-fluoro-3-trifluoromethylphenoxy)butanoic amide and herbicidal composition containing the same UBE INDUSTRIES, LTD. (JP) 1990-05-29 US disclosed
EP-0239414-B1 N-BENZYL-2-(4-FLUORO-3-TRIFLUOROMETHYLPHENOXY) BUTANOIC AMIDE AND HERBICIDAL COMPOSITION CONTAINING THE SAME UBE INDUSTRIES, LTD. (JP) 1989-11-02 EP disclosed
CN-1034918-A Chemical compound ICI PLC (GB) 1989-08-23 CN disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
US-4770991-A HIGH SPEED GIVING HIGH CONTRAST AND HIGH MAXIMUM DENSITY IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
US-4101481-A AN AMIDE TO PROVIDE AGING RESISTANCE SOCIETE DISTUGIL (FR) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS GLP1R, GIPR, IAPP ALDH1A1 4570/4885TSHR 100/4885NPSR1 597/4885
US-20080161325-A1 e.g. N1-[3-amino-4-(3,5-difluorophenyl)-2-hydroxybutyl]-3-(butylsulfonyl)-N1-(3-ethylbenzyl)-D-alaninamide dihydrochloride; inhibitors of amyloid beta-secretase enzyme; neurodegenerative diseases: Alzheimer's, Parkinson's diseases, Down's syndrome BACE1, APP, BACE2 ALDH1A1 2178/4885TSHR 4721/4885NPSR1 529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.