Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829150 | 0.83 | SLC18A3 (0.45) | FAAHESR2TBK1MAT2APDE3B | |
| SCHEMBL14336823 | 0.78 | KDM1A (0.31) | ESR2HTR2C | |
| SCHEMBL14336997 | 0.75 | MAT2A (0.45) | ESR2TBK1MAT2ASLC18A3FFAR1 | |
| SCHEMBL5239393 | 0.75 | MAT2A (0.45) | ESR2TBK1MAT2ASLC18A3FFAR1 | |
| SCHEMBL9715313 | 0.73 | ESR2 (0.61) | FAAHESR2TBK1MAT2APDE3B | |
| SCHEMBL6075905 | 0.72 | TSHR (0.35) | CNR1CNR2HTR1AHTR7 | |
| SCHEMBL19297360 | 0.72 | HTR2C (0.43) | FAAHESR2TBK1MAT2APDE3B | |
| SCHEMBL11833545 | 0.72 | ESR2 (0.42) | FAAHESR2TBK1MAT2APDE3B | |
| SCHEMBL11841493 | 0.72 | ESR2 (0.42) | FAAHESR2TBK1MAT2APDE3B | |
| SCHEMBL18905381 | 0.72 | ESR2 (0.42) | FAAHESR2TBK1MAT2APDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304076-B2 | Neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-04 | — | — | US | disclosed |
| US-7304076-B2 | Neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-04 | — | — | US | disclosed |