SCHEMBL9715313

SCHEMBL9715313

Oc1ccc(C2=CCC(O)CC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 6/20 0.61
QDPR P09417 2/20 0.44
ESR1 P03372 3/20 0.39
DRD2 P14416 3/20 0.37
DRD3 P35462 3/20 0.37
DRD4 P21917 2/20 0.37
TBK1 Q9UHD2 1/20 0.37
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
MAT2A P31153 1/20 0.34
FFAR1 O14842 1/20 0.34
KDM1A O60341 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11841493 0.82 ESR2 (0.42) ESR2QDPRTBK1PDE3BPDE3A
SCHEMBL11833545 0.82 ESR2 (0.42) ESR2TBK1PDE3BPDE3AMAT2A
SCHEMBL11829150 0.82 SLC18A3 (0.45) ESR2TBK1PDE3BPDE3AMAT2A
SCHEMBL19297360 0.82 HTR2C (0.43) ESR2TBK1PDE3BPDE3AMAT2A
SCHEMBL18905381 0.82 ESR2 (0.42) ESR2TBK1PDE3BPDE3AMAT2A
SCHEMBL14336997 0.82 MAT2A (0.45) ESR2TBK1MAT2AFFAR1
SCHEMBL503196 0.82 ESR2 (0.62) ESR2QDPRESR1DRD2DRD3
SCHEMBL5239393 0.82 MAT2A (0.45) ESR2TBK1MAT2AFFAR1
SCHEMBL10930951 0.78 ESR2 (0.59) ESR2QDPRESR1DRD2DRD3
SCHEMBL11839749 0.78 PDE3B (0.43) ESR2PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287290-B1 PREPARATION PROCESS OF 4,4'-BIPHENOL, PRECURSOR OF SAME AND PREPARATION PROCESS OF PRECURSOR MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-07-08 EP claimed
EP-0303398-B1 PREPARATION PROCESS OF 4-(4-HYDROXYPHENYL)-CYCLOHEXANOL MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-11 EP claimed
US-4939306-A Dehydrogevation by catalysis of 4-(4-hydroxyphenyl)-3-cyclohexene-1-ol by-product inhibition MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-07-03 US claimed
US-4894487-A Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-01-16 US claimed
US-4877907-A DEHYDROGENATION OF 4-(4-HYDROXYPHENYL)-3-CYCLOHEXENE-1-OL MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-10-31 US claimed
US-4873374-A 4-(4-HYDROXYPHENYL)-3-CYCLOHEXENE-1-OL INTERMEDIATE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-10-10 US claimed
EP-0303398-A1 Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-02-15 EP claimed
EP-0287290-A1 Preparation process of 4,4'-biphenol, precursor of same and preparation process of precursor MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-10-19 EP claimed
JP-1047727-A None JP disclosed
JP-1250334-A None JP disclosed
EP-0287290-B1 PREPARATION PROCESS OF 4,4'-BIPHENOL, PRECURSOR OF SAME AND PREPARATION PROCESS OF PRECURSOR MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-07-08 EP disclosed
EP-0303398-B1 PREPARATION PROCESS OF 4-(4-HYDROXYPHENYL)-CYCLOHEXANOL MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-11 EP disclosed
US-4939306-A Dehydrogevation by catalysis of 4-(4-hydroxyphenyl)-3-cyclohexene-1-ol by-product inhibition MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-07-03 US disclosed
US-4939306-A Dehydrogevation by catalysis of 4-(4-hydroxyphenyl)-3-cyclohexene-1-ol by-product inhibition MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-07-03 US disclosed
JP-H01250334-A PRODUCTION OF 4,4'-BIPHENOL, PRECURSOR THEREOF AND PRODUCTION OF SAID PRECURSOR MITSUI TOATSU CHEM INC 1989-10-05 JP disclosed
JP-S6447727-A PRODUCTION OF 4-(4-HYDROXYPHENYL)-CYCLOHEXANOL MITSUI TOATSU CHEMICALS 1989-02-22 JP disclosed
EP-0303398-A1 Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-02-15 EP disclosed
EP-0303398-A1 Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-02-15 EP disclosed
EP-0287290-A1 Preparation process of 4,4'-biphenol, precursor of same and preparation process of precursor MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-10-19 EP disclosed
EP-0287290-A1 Preparation process of 4,4'-biphenol, precursor of same and preparation process of precursor MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-10-19 EP disclosed