SCHEMBL14337337

SCHEMBL14337337

C=Nc1cc(C)cc(C(C)(C)C)c1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.63
CA2 P00918 4/20 0.63
ALDH1A1 P00352 4/20 0.63
POLB P06746 1/20 0.63
TYR P14679 1/20 0.63
HSPA5 P11021 1/20 0.52
CYP2C9 P11712 4/20 0.50
CYP2C19 P33261 4/20 0.50
HIF1A Q16665 4/20 0.50
CYP2D6 P10635 2/20 0.45
HSD17B10 Q99714 1/20 0.45
CA1 P00915 2/20 0.43
CYP1A2 P05177 3/20 0.42
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
NPSR1 Q6W5P4 2/20 0.39
HTT P42858 2/20 0.39
MAPT P10636 3/20 0.38
ALOX15 P16050 2/20 0.38
HPN P05981 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14337261 0.81 CA2 (0.43) SMN1; SMN2CA2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL27955719 0.79 SMN1; SMN2 (0.90) SMN1; SMN2CA2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL453824 0.79 SMN1; SMN2 (1.00) SMN1; SMN2CA2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL3950 0.79 SMN1; SMN2 (1.00) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL14337336 0.78 SMN1; SMN2 (0.59) SMN1; SMN2CA2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL11859223 0.77 SMN1; SMN2 (0.95) SMN1; SMN2CA2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL11857289 0.77 SMN1; SMN2 (0.95) SMN1; SMN2CA2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL864242 0.77 SMN1; SMN2 (0.95) SMN1; SMN2CA2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL7075597 0.77 SMN1; SMN2 (0.95) SMN1; SMN2CA2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL20660368 0.77 SMN1; SMN2 (0.95) SMN1; SMN2CA2ALDH1A1POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed