SCHEMBL14337136

SCHEMBL14337136

O=C(Oc1ccccc1)c1cccc(/C=N/c2ccccc2)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
KDM4E B2RXH2 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
HPGD P15428 2/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAOB P27338 5/20 0.46
MAOA P21397 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
ALDH1A1 P00352 2/20 0.42
NSD2 O96028 1/20 0.41
TLR2 O60603 1/20 0.41
TLR1 Q15399 1/20 0.41
TLR6 Q9Y2C9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14337485 0.81 MAPT (0.56) MAPTKDM4EHPGDALOX15HSD17B10
SCHEMBL5087773 0.81 HSD17B10 (0.57) MAPTKDM4ETDP1HPGDALOX15
SCHEMBL14337415 0.80 SIRT2 (0.50) MAPTKDM4EHPGDMAOBMAOA
SCHEMBL11428245 0.79 MAPT (0.47) MAPTKDM4ETDP1HPGDALOX15
SCHEMBL14337414 0.78 SIRT2 (0.49) MAOBMAOASIRT2AKR1C3AKR1C2
SCHEMBL5712255 0.78 HSD17B10 (0.71) MAPTKDM4ETDP1HPGDALOX15
SCHEMBL2148267 0.77 HSD17B10 (0.53) MAPTKDM4ETDP1HPGDALOX15
SCHEMBL2148269 0.77 HSD17B10 (0.53) MAPTKDM4ETDP1HPGDALOX15
SCHEMBL14337134 0.76 SIRT2 (0.46) MAPTKDM4EHPGDMAOBMAOA
SCHEMBL9381488 0.75 CA1 (0.55) MAPTKDM4EHPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170308-B1 Process for producing a copolymer of a non-polar olefin and a polar olefin MITSUI CHEMICALS INC (JP) 2015-05-06 EP disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed