SCHEMBL14337648

SCHEMBL14337648

Cc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4cccc(C)c4)c(C)c3)cc2C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 4/20 0.38
HSD17B2 P37059 4/20 0.38
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
ALDH1A1 P00352 4/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP2C19 P33261 3/20 0.33
ACHE P22303 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
PAX8 Q06710 2/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
JAK2 O60674 1/20 0.33
HTT P42858 1/20 0.33
THRB P10828 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7768344 0.97 HSD17B1 (0.39) HSD17B1HSD17B2ALDH1A1HPGDALOX15
SCHEMBL13136840 0.95 HSD17B1 (0.41) HSD17B1HSD17B2ALDH1A1HPGDALOX15
SCHEMBL2389195 0.95 HSD17B1 (0.40) HSD17B1HSD17B2SLC6A2SLC6A4ALDH1A1
SCHEMBL12463077 0.94 HSD17B1 (0.43) HSD17B1HSD17B2SLC6A2SLC6A4ALDH1A1
SCHEMBL8365893 0.94 HSD17B1 (0.40) HSD17B1HSD17B2SLC6A2SLC6A4ALDH1A1
SCHEMBL14732535 0.92 CYP2C19 (0.38) ALDH1A1HPGDCYP2C19ACHENPC1
SCHEMBL7764386 0.92 CYP2C19 (0.38) ALDH1A1HPGDCYP2C19ACHENPC1
SCHEMBL23937009 0.91 HSD17B1 (0.38) HSD17B1HSD17B2SLC6A2SLC6A4ALDH1A1
SCHEMBL13136846 0.91 CYP2C19 (0.37) ALDH1A1HPGDCYP2C19ACHENPC1
SCHEMBL29462709 0.91 HSD17B1 (0.43) HSD17B1HSD17B2SLC6A2SLC6A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309557-B2 Image forming apparatus and image forming method KONICA MINOLTA HOLDINGS, INC. (JP) 2007-12-18 US disclosed
US-7309557-B2 Image forming apparatus and image forming method KONICA MINOLTA HOLDINGS, INC. (JP) 2007-12-18 US disclosed