SCHEMBL7764386

SCHEMBL7764386

Cc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(C)cc4)c(C)c3)cc2C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.38
APP P05067 1/20 0.36
ALDH1A1 P00352 5/20 0.35
TDP1 Q9NUW8 4/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPT P10636 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
HPGD P15428 2/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
TSHR P16473 3/20 0.34
LMNA P02545 1/20 0.34
ALOX12 P18054 1/20 0.34
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14732535 1.00 CYP2C19 (0.38) CYP2C19APPALDH1A1TDP1KDM4E
SCHEMBL13136846 0.98 CYP2C19 (0.37) CYP2C19APPALDH1A1TDP1KDM4E
SCHEMBL15041103 0.97 ALDH1A1 (0.37) CYP2C19APPALDH1A1TDP1KDM4E
SCHEMBL12533878 0.95 MEN1 (0.38) CYP2C19ALDH1A1TDP1KDM4EMAPT
SCHEMBL19826255 0.95 MEN1 (0.38) CYP2C19ALDH1A1TDP1KDM4EMAPT
SCHEMBL14732542 0.95 MEN1 (0.38) CYP2C19ALDH1A1TDP1KDM4EMAPT
SCHEMBL7613942 0.95 MEN1 (0.38) CYP2C19ALDH1A1TDP1KDM4EMAPT
SCHEMBL8638695 0.93 ALDH1A1 (0.38) CYP2C19APPALDH1A1TDP1KDM4E
SCHEMBL7768070 0.93 ALDH1A1 (0.37) CYP2C19APPALDH1A1TDP1KDM4E
SCHEMBL142025 0.93 ALDH1A1 (0.39) CYP2C19ALDH1A1TDP1MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-7955768-B2 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2011-06-07 US disclosed
US-7955768-B2 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2011-06-07 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
EP-0863441-B1 Electrophotographic imaging member XEROX CORP (US) 2001-06-20 EP disclosed
US-6127077-A Photoreceptors with delayed discharge XEROX CORPORATION (US) 2000-10-03 US disclosed
EP-0529878-B1 Photoreceptor containing similar charge transporting small molecule and charge transporting polymer XEROX CORP (US) 1997-02-26 EP disclosed
EP-0529877-B1 Photoreceptor containing dissimilar charge transporting small molecule and charge transporting polymer XEROX CORP (US) 1996-11-13 EP disclosed
EP-0434368-B1 Electrophotographic imaging members XEROX CORP (US) 1996-04-03 EP disclosed
US-5476968-A Formylation with a substituted formamide and an acid chloride; reduction with a borohydride or aluminum hydride salt FUJI XEROX CO., LTD. (JP) 1995-12-19 US disclosed
US-5316880-A Multilayer electrography imaging member with charge generating and charge transport layers on films XEROX CORPORATION (US) 1994-05-31 US disclosed
EP-0529877-A1 Photoreceptor containing dissimilar charge transporting small molecule and charge transporting polymer XEROX CORPORATION (US) 1993-03-03 EP disclosed
EP-0529878-A1 Photoreceptor containing similar charge transporting small molecule and charge transporting polymer XEROX CORPORATION (US) 1993-03-03 EP disclosed
US-5028502-A Charge Transport Layer Containing Polystyrene Film Forming Binder And An Aromatic Diamine Or Hydrazone Compound XEROX CORPORATION (US) 1991-07-02 US disclosed
EP-0434368-A2 Electrophotographic imaging members XEROX CORPORATION (US) 1991-06-26 EP disclosed
US-4988595-A MULTILAYER ELECTROPHOTOGRAPHIC IMAGING MEMBER, CHARGE TRANSPORT LAYER AND CHARGE GENERATING COMPOUND XEROX CORPORATION (US) 1991-01-29 US disclosed