SCHEMBL14337677

SCHEMBL14337677

O=C(O)C1Cc2ccccc2CN1c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.58
JAK2 O60674 1/20 0.58
ACE P12821 3/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
POLB P06746 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
APOBEC3A P31941 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
MMP8 P22894 3/20 0.42
MMP3 P08254 2/20 0.42
MMP13 P45452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14564575 0.85 CHEK1 (0.55) CHEK1JAK2ACEALDH1A1LMNA
SCHEMBL7534425 0.83 CHEK1 (0.62) CHEK1JAK2ACEALDH1A1POLB
SCHEMBL7534430 0.83 CHEK1 (0.62) CHEK1JAK2ACEALDH1A1POLB
SCHEMBL30904650 0.83 CHEK1 (0.52) CHEK1JAK2ACELMNAPOLB
SCHEMBL7746086 0.80 ACE (0.52) CHEK1JAK2ACEALDH1A1LMNA
SCHEMBL14398074 0.77 CHEK1 (0.50) CHEK1JAK2ACEALDH1A1LMNA
SCHEMBL13971489 0.77 ACE (0.54) CHEK1JAK2ACEALDH1A1LMNA
SCHEMBL3154327 0.77 ACE (0.54) CHEK1JAK2ACEALDH1A1LMNA
SCHEMBL8908771 0.77 ACE (0.61) CHEK1JAK2ACEALDH1A1LMNA
SCHEMBL4573235 0.77 ACE (0.61) CHEK1JAK2ACEALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312022-B2 Developing solution contains a heterocyclic compound having three or more heteroatoms which when added, capable of enhancing the sensitivity of the silver halide color photosensitive material; high sensitivity, excellent color image storability FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
US-7306900-B2 Silver halide color photosensitive material FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-20070254249-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2007-11-01 US disclosed
US-7264920-B2 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-09-04 US disclosed
US-20070178417-A1 Photothermographic material and an image forming method FUJIFILM CORPORATION (JP) 2007-08-02 US disclosed
US-7244551-B2 Silver halide color photosensitive material FUJIFILM CORPORATION (JP) 2007-07-17 US disclosed
US-7214476-B2 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2007-05-08 US disclosed
US-7208264-B2 Photothermographic material and method of forming images FUJIFILM CORPORATION (JP) 2007-04-24 US disclosed
US-20070077527-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. 2007-04-05 US disclosed
US-7172857-B2 Image forming photosensitive silver halide, a nonphotosensitive organic silver salt, reducing agent, and binder; shell-core polymer on support; storage stability; adhesion resistance, photography FUJIFILM CORPORATION (JP) 2007-02-06 US disclosed
US-20070026349-A1 when parallel light having the same wavelength as a main emission peak wavelength of the fluorescent intensifying screen is incident perpendicular to the material surface, the parallel light component of transmitted light comprises 5% or more of the incident light; for medical use having high sensitivity FUJI PHOTO FILM CO., LTD. 2007-02-01 US disclosed