Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677334 | 1.00 | TDP1 (0.52) | TDP1MAPK1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL14645485 | 0.93 | TDP1 (0.50) | TDP1MAPK1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL13321986 | 0.93 | TDP1 (0.50) | TDP1MAPK1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1356320 | 0.91 | ALDH1A1 (0.50) | TDP1MAPK1ALDH1A1CYP3A4CA2 | |
| SCHEMBL18493494 | 0.91 | TDP1 (0.46) | TDP1MAPK1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL17203010 | 0.91 | TDP1 (0.46) | TDP1MAPK1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1357035 | 0.91 | ALDH1A1 (0.50) | TDP1MAPK1ALDH1A1CYP3A4CA2 | |
| SCHEMBL15496895 | 0.89 | MAPK1 (0.48) | TDP1MAPK1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL20173388 | 0.87 | KDM4E (0.52) | TDP1MAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL28700702 | 0.86 | KDM1A (0.46) | TDP1MAPK1KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070278455-A1 | Polymer compound and organic light-emitting device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2007-12-06 | — | — | US | disclosed |