SCHEMBL28700702

SCHEMBL28700702

CCCCC(CC)COc1ccc2cc(Br)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44
LMNA P02545 3/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPK1 P28482 5/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 4/20 0.40
CYP2D6 P10635 1/20 0.40
ALDH1A1 P00352 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CA2 P00918 1/20 0.40
TSHR P16473 1/20 0.39
USP2 O75604 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22499622 0.91 TDP1 (0.46) LMNAMAPK1TDP1CYP3A4ALDH1A1
SCHEMBL3415870 0.88 TDP1 (0.44) LMNAMAPK1TDP1CYP3A4ALDH1A1
SCHEMBL14337698 0.86 TDP1 (0.52) LMNAMAPTHTTSMN1; SMN2MEN1
SCHEMBL677334 0.86 TDP1 (0.52) LMNAMAPTHTTSMN1; SMN2MEN1
SCHEMBL18837355 0.85 CA2 (0.48) KDM1ALMNAMAPK1TDP1KDM4E
SCHEMBL26987629 0.84 MAOB (0.44) LMNAMAPTKMT2AMAPK1KDM4E
SCHEMBL4268288 0.83 LMNA (0.40) KDM1ALMNAMAPTSMN1; SMN2MAPK1
SCHEMBL27970285 0.82 TDP1 (0.42) LMNAMAPK1TDP1KDM4ECYP3A4
SCHEMBL1357035 0.81 ALDH1A1 (0.50) LMNAMAPK1TDP1CYP3A4ALDH1A1
SCHEMBL1356320 0.81 ALDH1A1 (0.50) LMNAMAPK1TDP1CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163443-A Compound, liquid crystal composition, and liquid crystal display element or light control element DIC株式会社 2022-03-11 CN disclosed