SCHEMBL14339477

SCHEMBL14339477

N[C@@H]1[C@H]2CN(c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)C[C@@H]12

nearest known ligand 0.75

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 16/20 0.75
MAOB P27338 1/20 0.75
KCNH2 Q12809 1/20 0.66
CYP3A4 P08684 3/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5459647 1.00 MAOA (0.75) MAOAMAOBKCNH2CYP3A4CYP2D6
SCHEMBL14480152 0.89 MAOA (0.78) MAOAMAOBKCNH2CYP3A4CYP2D6
SCHEMBL6486990 0.89 MAOA (0.78) MAOAMAOBKCNH2CYP3A4CYP2D6
SCHEMBL5238909 0.88 MAOA (0.80) MAOAMAOBKCNH2CYP3A4CYP2D6
SCHEMBL5320223 0.88 MAOA (0.80) MAOAMAOBKCNH2CYP3A4CYP2D6
SCHEMBL14339464 0.87 MAOA (0.59) MAOAMAOBKCNH2CYP3A4CYP2D6
SCHEMBL5468241 0.87 MAOA (0.59) MAOAMAOBKCNH2CYP3A4CYP2D6
SCHEMBL5235201 0.87 MAOA (0.75) MAOAMAOBKCNH2CYP3A4CYP2D6
SCHEMBL5229435 0.87 MAOA (0.75) MAOAMAOBKCNH2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL5230780 0.86 MAOA (0.74) MAOAMAOBKCNH2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070293493-A1 OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF KYORIN PHARMACEUTICAL CO., LTD. (JP) 2007-12-20 US disclosed
US-20070293493-A1 OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF KYORIN PHARMACEUTICAL CO., LTD. (JP) 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293493-A1 OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF OXA1L, RORC, IL17A MAOA 3244/4885MAOB 2243/4885KCNH2 3653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.