Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14339484 | 0.95 | PHLPP2 (0.42) | ENPP2PTPN11PHLPP2BRD4MEN1 | |
| SCHEMBL14339486 | 0.91 | PTPN11 (0.39) | ENPP2PTPN11PHLPP2BRD4MEN1 | |
| SCHEMBL14339482 | 0.86 | ENPP2 (0.44) | ENPP2PTPN11PHLPP2MEN1ALDH1A1 | |
| SCHEMBL13615130 | 0.86 | PTPN11 (0.46) | ENPP2PTPN11PHLPP2MEN1ALDH1A1 | |
| SCHEMBL13615190 | 0.85 | PHLPP2 (0.46) | ENPP2PTPN11PHLPP2BRD4MEN1 | |
| SCHEMBL14351159 | 0.84 | ENPP2 (0.53) | ENPP2PHLPP2BRD4MEN1ALDH1A1 | |
| SCHEMBL14351144 | 0.83 | PHLPP2 (0.52) | ENPP2PHLPP2BRD4MEN1ALDH1A1 | |
| SCHEMBL13615319 | 0.82 | ENPP2 (0.40) | ENPP2PTPN11PHLPP2MEN1ALDH1A1 | |
| SCHEMBL13860946 | 0.82 | ENPP2 (0.46) | ENPP2PTPN11PHLPP2BRD4MEN1 | |
| SCHEMBL13921652 | 0.82 | PHLPP2 (0.42) | ENPP2PTPN11PHLPP2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287830-A1 | Trisazo Dye, Composition Containing the Same for Anisotropic Dye Film, Anisotropic Dye Film, and Polarizing Element | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-12-13 | — | — | US | disclosed |