SCHEMBL13615319

SCHEMBL13615319

COc1cc(/N=N/c2c(SOOO)cc3cc(S(=O)(=O)O)c(N)cc3c2O)c(OC)cc1/N=N/c1ccc2[nH]c(=O)[nH]c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 7/20 0.40
PHLPP2 Q6ZVD8 1/20 0.39
MEN1 O00255 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
MAPK1 P28482 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
PTPN11 Q06124 1/20 0.36
PTK6 Q13882 4/20 0.35
EGFR P00533 1/20 0.35
FYN P06241 1/20 0.35
BMX P51813 1/20 0.35
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615307 0.89 PTPN11 (0.41) ENPP2PHLPP2MEN1ALDH1A1KMT2A
SCHEMBL13629264 0.89 ENPP2 (0.48) ENPP2PHLPP2MEN1ALDH1A1MAPT
SCHEMBL13615301 0.87 SENP3 (0.41) ENPP2PHLPP2MEN1ALDH1A1KMT2A
SCHEMBL13615190 0.87 PHLPP2 (0.46) ENPP2PHLPP2MEN1ALDH1A1MAPT
SCHEMBL13615130 0.85 PTPN11 (0.46) ENPP2PHLPP2MEN1ALDH1A1MAPT
SCHEMBL13615290 0.85 PTPN11 (0.47) ENPP2PHLPP2MEN1MAPTKMT2A
SCHEMBL13615299 0.84 ENPP2 (0.32) ENPP2PTPN11
SCHEMBL13615293 0.84 ENPP2 (0.44) ENPP2PHLPP2MEN1ALDH1A1MAPT
SCHEMBL13615302 0.84 PHLPP2 (0.42) ENPP2PHLPP2MEN1ALDH1A1MAPT
SCHEMBL13921652 0.83 PHLPP2 (0.42) ENPP2PHLPP2MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275742-A1 COLORING MATTER FOR ANISOTROPIC COLORING MATTER FILM, COMPOSITION COMPRISING SAID COLORING MATTER, ANISOTROPIC COLORING MATTER FILM, AND POLARIZING ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2009-11-05 US disclosed