Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14340774 | 0.85 | RAB9A (0.41) | PANK3KDM4ERAB9AMEN1PSMD14 | |
| SCHEMBL14340775 | 0.83 | SMO (0.41) | KDM4ERAB9AKMT2APOLBMAPT | |
| SCHEMBL390397 | 0.78 | MAPT (0.41) | PANK3KDM4ERAB9AMEN1PSMD14 | |
| SCHEMBL387763 | 0.72 | DGAT1 (0.41) | PANK3KDM4ERAB9AMEN1PSMD14 | |
| SCHEMBL14340920 | 0.72 | SMO (0.43) | KDM4ERAB9AKMT2ANPC1TSHR | |
| SCHEMBL10168035 | 0.71 | PANK3 (0.45) | PANK3KDM4ERAB9AMEN1PSMD14 | |
| SCHEMBL387209 | 0.71 | PANK3 (0.54) | PANK3KDM4ERAB9AMEN1PSMD14 | |
| SCHEMBL388867 | 0.70 | PANK3 (0.38) | PANK3KDM4ERAB9AMEN1PSMD14 | |
| SCHEMBL389707 | 0.69 | — | — | |
| SCHEMBL387218 | 0.68 | PANK3 (0.43) | PANK3KDM4ERAB9AMEN1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870401-A1 | 1,4-SUBSTITUTED PIPERAZINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-12-26 | — | — | EP | disclosed |