Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149916 | 0.76 | EPHX2 (0.67) | EPHX2EPHX1SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL13745657 | 0.75 | EPHX2 (0.43) | EPHX2EPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL6879513 | 0.74 | HSD11B1 (0.42) | — | |
| SCHEMBL8063391 | 0.74 | HSD11B1 (0.42) | — | |
| SCHEMBL8060470 | 0.74 | HSD11B1 (0.42) | — | |
| SCHEMBL12517573 | 0.73 | EPHX2 (0.61) | EPHX2HTT | |
| SCHEMBL8025935 | 0.73 | GRIN2D (0.52) | — | |
| SCHEMBL13768759 | 0.72 | EPHX2 (0.57) | EPHX2EPHX1 | |
| SCHEMBL13126732 | 0.72 | EPHX2 (0.43) | EPHX2EPHX1SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL13768777 | 0.71 | EPHX2 (0.56) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272458-B1 | ARGININE MIMETICS AS FACTOR XA INHIBITORS | WILEX AG (DE) | 2007-12-05 | — | — | EP | disclosed |