Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14340973 | 0.75 | EPHX2 (0.40) | EPHX2ALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL14413585 | 0.72 | EPHX2 (0.46) | EPHX2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4516091 | 0.70 | EPHX2 (0.67) | EPHX2ALDH1A1TSHREPHX1LMNA | |
| SCHEMBL3920461 | 0.70 | EPHX2 (0.55) | EPHX2ALDH1A1TSHREPHX1MEN1 | |
| SCHEMBL13768759 | 0.70 | EPHX2 (0.57) | EPHX2EPHX1 | |
| SCHEMBL13768777 | 0.69 | EPHX2 (0.56) | EPHX2EPHX1 | |
| SCHEMBL2638872 | 0.69 | EPHX2 (0.57) | EPHX2ALDH1A1TSHREPHX1MEN1 | |
| SCHEMBL8025935 | 0.69 | GRIN2D (0.52) | — | |
| SCHEMBL10138566 | 0.69 | EPHX2 (0.44) | EPHX2EPHX1 | |
| SCHEMBL13768396 | 0.69 | EPHX2 (0.74) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |