SCHEMBL1434166

SCHEMBL1434166

CC(=O)Nc1nc2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
CYP3A4 P08684 1/20 0.71
NPC1 O15118 11/20 0.67
RAB9A P51151 10/20 0.67
SMN1; SMN2 Q16637 6/20 0.67
PKM P14618 4/20 0.67
MAOB P27338 1/20 0.67
ADORA2A P29274 1/20 0.67
OPRK1 P41145 1/20 0.64
KLF5 Q13887 1/20 0.64
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
ALDH1A1 P00352 2/20 0.61
HSD17B10 Q99714 2/20 0.61
MAPK1 P28482 1/20 0.61
TP53 P04637 3/20 0.60
SCD O00767 1/20 0.60
GAA P10253 1/20 0.60
POLB P06746 1/20 0.60
TDP1 Q9NUW8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30968980 1.00 LMNA (1.00) LMNACYP3A4NPC1RAB9ASMN1; SMN2
SCHEMBL23566380 0.86 NPC1 (0.75) LMNACYP3A4NPC1RAB9ASMN1; SMN2
SCHEMBL20685429 0.85 LMNA (0.73) LMNACYP3A4NPC1RAB9ASMN1; SMN2
SCHEMBL204726 0.84 NPC1 (0.73) LMNACYP3A4NPC1RAB9ASMN1; SMN2
SCHEMBL6234451 0.84 LMNA (0.72) LMNACYP3A4NPC1RAB9ASMN1; SMN2
SCHEMBL10094298 0.84 LMNA (0.72) LMNACYP3A4NPC1RAB9ASMN1; SMN2
Carbendazim SCHEMBL21051 0.83 LMNA (0.71) LMNACYP3A4NPC1RAB9ASMN1; SMN2
SCHEMBL3498883 0.83 LMNA (0.71) LMNACYP3A4NPC1RAB9ASMN1; SMN2
Carbendazim SCHEMBL29357746 0.83 LMNA (0.71) LMNACYP3A4NPC1RAB9ASMN1; SMN2
Carbendazim SCHEMBL8427009 0.83 LMNA (0.71) LMNACYP3A4NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002086254-A1 STRUCTURE FOR ROUNDING A CORNER OF WALLS BION21 INC. (KR) 2002-10-31 WO claimed
US-6300395-B1 PREVENTS OFFENSIVE ODOR GENERATION, ANTIBACTERIAL PERFORMANCE AND FORMABILITY NIKON PARKERIZING, CO., LTD. (JP) 2001-10-09 US claimed
EP-0157146-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-09-27 EP claimed
EP-0126433-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-03-22 EP claimed
US-4698297-A INCLUDING A CHEMICALLY STABLE COMPOUND ABLE TO RELEASE A USEFUL CONTROLLABLE GROUP HAVING GOOD DIFFUSION; SHARPNESS FUJI PHOTO FILM CO., LTD. (JP) 1987-10-06 US claimed
US-4618571-A STORAGE-STABLE COUPLERS; CONTROLLED-RELEASABLE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1986-10-21 US claimed
US-4565777-A Silver halide color photographic light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1986-01-21 US claimed
EP-0157146-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-10-09 EP claimed
US-4526861-A Heterocyclic ring contains imide or sulfonamide group FUJI PHOTO FILM CO., LTD. (JP) 1985-07-02 US claimed
US-4511649-A Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US claimed
EP-0126433-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-11-28 EP claimed
JP-5156035-A None JP disclosed
JP-60034895-A None JP disclosed
JP-3050260-A None JP disclosed
JP-11276985-A None JP disclosed
EP-0107112-A2 Silver halide color photographic light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1984-05-02 EP disclosed
EP-0101621-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1984-02-29 EP disclosed
US-4241168-A TWO-EQUIVALENT MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-12-23 US disclosed
US-4072525-A COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1978-02-07 US disclosed
US-4032346-A 5-OXO-2-PYRAZOLIN-4-YL-AMINE-CARBODITHIOATE-DITHIOCARBONATE FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US disclosed