⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181011 | 0.81 | CA2 (0.43) | — | |
| SCHEMBL6622409 | 0.78 | CA2 (0.47) | — | |
| SCHEMBL14370093 | 0.76 | HRH3 (0.50) | — | |
| SCHEMBL4071544 | 0.76 | CYP3A4 (0.50) | — | |
| SCHEMBL3674028 | 0.74 | — | — | |
| SCHEMBL2932220 | 0.74 | — | — | |
| SCHEMBL10839040 | 0.74 | GPR84 (0.47) | — | |
| SCHEMBL3672063 | 0.74 | — | — | |
| SCHEMBL904427 | 0.74 | — | — | |
| SCHEMBL904600 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232209-B2 | Processes for forming electronic devices including polishing metal-containing layers | SPANSION LLC (US) | 2012-07-31 | — | — | US | claimed |
| US-8148537-B2 | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA A/S (DK) | 2012-04-03 | — | — | US | claimed |
| US-20110136268-A1 | PROCESSES FOR FORMING ELECTRONIC DEVICES INCLUDING POLISHING METAL-CONTAINING LAYERS | SPANSION LLC (US) | 2011-06-09 | — | — | US | claimed |
| EP-2125736-B1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA AS (DK) | 2011-03-30 | — | — | EP | claimed |
| US-7915169-B2 | Processes for forming electronic devices including polishing metal-containing layers | SPANSION LLC (US) | 2011-03-29 | — | — | US | claimed |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA (DK) | 2010-02-11 | — | — | US | claimed |
| US-20090117734-A1 | PROCESSES FOR FORMING ELECTRONIC DEVICES INCLUDING POLISHING METAL-CONTAINING LAYERS | SPANSION LLC (US) | 2009-05-07 | — | — | US | claimed |
| US-20240018131-A1 | MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF USE THEREOF | FORESEE PHARMACEUTICALS USA, INC. | 2024-01-18 | — | — | US | disclosed |
| US-11739080-B2 | Matrix metalloproteinase (MMP) inhibitors and methods of use thereof | FORESEE PHARMACEUTICALS USA, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| EP-2970224-B1 | TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS | ONYX THERAPEUTICS INC (US) | 2017-09-06 | — | — | EP | disclosed |
| WO-2014152134-A1 | TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS | ONYX THERAPEUTICS, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-2763966-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| US-8497380-B2 | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA A/S (DK) | 2013-07-30 | — | — | US | disclosed |
| US-6043248-A | VIRICIDES FOR TREATING AN INDIVIDUAL INFECTED WITH THE HUMAN IMMUNODEFICIENCY VIRUS | PHARMACIA & UPJOHN COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| US-5837321-A | VAPOR DEPOSITION USING YTTRIUM DIKETONATE/PYRIDINE N-OXIDE ADDUCT | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1998-11-17 | — | — | US | disclosed |
| CN-1183773-A | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | UPJOHN CO (US) | 1998-06-03 | — | — | CN | disclosed |
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035678-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |
| WO-1995014698-A1 | VOLATILE ORGANIC LANTHANIDE COMPOUNDS AND METHODS FOR THE PREPARATION OF LANTHANIDE-CONTAINING LAYERED MATERIALS FROM THESE COMPOUNDS | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1995-06-01 | — | — | WO | disclosed |
| US-4066459-A | IMINE COMPOUNDS | HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) | 1978-01-03 | — | — | US | disclosed |