Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.59 |
| ▸ | CA12 | O43570 | 12/20 | 0.59 |
| ▸ | CA1 | P00915 | 12/20 | 0.59 |
| ▸ | CA9 | Q16790 | 6/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 6/20 | 0.52 |
| ▸ | CA5A | P35218 | 6/20 | 0.52 |
| ▸ | CA7 | P43166 | 6/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18649161 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL10936126 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL17030496 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL1682155 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL13707324 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL19976655 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL18102344 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL13163793 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL5497115 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 | |
| SCHEMBL7151293 | 1.00 | CA2 (0.59) | CA2CA12CA1CA9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159592-A1 | PCSK9 ANTAGONIST COMPOUNDS | MERCK SHARP & DOHME LLC | 2023-05-25 | — | — | US | disclosed |
| US-10273260-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2019-04-30 | — | — | US | disclosed |
| US-20170247401-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY | 2017-08-31 | — | — | US | disclosed |
| US-9567362-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2017-02-14 | — | — | US | disclosed |
| US-7312194-B2 | Delivery systems | ALCHEMIA PTY. LTD. (AU) | 2007-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273260-B2 | Compounds and methods for treating bacterial infections | MMP8, ELANE, GUSB | CA2 409/4885CA12 335/4885CA1 1322/4885 |
| US-20230159592-A1 | PCSK9 ANTAGONIST COMPOUNDS | PCSK9, PCSK7, PCSK6 | CA2 4141/4885CA12 4125/4885CA1 4496/4885 |
| US-20170247401-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | MMP8, ELANE, GUSB | CA2 409/4885CA12 335/4885CA1 1322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.